Development of a Silver-Based Dual-Function Antimicrobial Laundry Additive and Textile Coating for the Decontamination of Healthcare Laundry
Aims: To repurpose a silver-based antimicrobial textile coating product (Micro-Fresh 1911) as a dual-function antimicrobial laundry additive and textile coating. Methods and Results: Survival of Escherichia coli or Staphylococcus aureus type and clinical isolates in a domestic 40°C wash was assessed with and without soiling and biological detergent. Washing with 2% w/v silver additive (wash phase) reduced E. coli and S. aureus by 7.14-8.08 log10 and no cross-contamination was observed. Under dirty conditions, 0.5% silver additive in the rinse phase of a wash with biological detergent reduced E. coli and S. aureus by 7.98-8.40 log10 (0.00-1.42 log10 cross contamination). ISO 20645:2006 and ISO 20743:2013 methods were used to assess the antimicrobial activity of polycotton washed with 2% w/v silver additive against S. aureus and E. coli. The treated polycotton was antimicrobial against E. coli and S. aureus type and clinical isolates and remains active after at least one further wash cycle at 40°C or 73°C. Conclusions: The silver additive exhibits antimicrobial activity in a 40°C domestic wash, preventing cross contamination onto clean textiles and depositing an antimicrobial coating onto polycotton. Significance and Impact of Study: The survival of microorganisms on healthcare uniforms during domestic laundering presents a potential risk of contaminating the home, cross-contamination of other clothing within the wash and transmitting potential pathogens back into healthcare settings via contaminated uniforms. Silver may be useful as an antimicrobial laundry additive to decontaminate healthcare laundry washed at low temperatures in domestic and industrial settings, to therefore reduce the potential risk of transmitting microorganisms within the domestic and clinical environments.
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.
Citation : Owen, L. and Laird, K. (2020) Development of a Silver-Based Dual-Function Antimicrobial Laundry Additive and Textile Coating for the Decontamination of Healthcare Laundry. Journal of Applied Microbiology.
Research Institute : Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)
Peer Reviewed : Yes
- Leicester School of Pharmacy