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dc.contributor.authorCanfarotta, Francesco
dc.contributor.authorPiletsky, Sergey
dc.contributor.authorTurner, Nicholas
dc.date.accessioned2020-02-04T10:29:46Z
dc.date.available2020-02-04T10:29:46Z
dc.date.issued2019-10-15
dc.identifier.citationCanfarotta, F., Piletsky, S.A., Turner, N.W. (2020) Generation of High-Affinity Molecularly Imprinted Nanoparticles for Protein Recognition via a Solid-Phase Synthesis Protocol. In: Gerrard, J., Domigan, L. (eds.) Protein Nanotechnology:Protocols, Instrumentation and Applications, Methods in Molecular Biology, vol 2073. New York NY: Humana.en
dc.identifier.isbn978-1-4939-9868-5
dc.identifier.urihttps://dora.dmu.ac.uk/handle/2086/19119
dc.description.abstractMolecularly imprinted polymers are leading technology in the development of protein biomimetics. This chapter describes the protocol for the synthesis of protein imprinted nanoparticles. These materials exhibit exceptional affinity (into the nM/pM range) and selectivity for their target template. The nanoparticles can be developed for a wide range of targets, while exhibiting excellent robustness, solubility, and flexibility in use. They are finding use in the creation of drug delivery vectors and sensing and recognition assays.en
dc.language.isoenen
dc.publisherHumanaen
dc.relation.ispartofseriesMethods in Molecular Biology;
dc.subjectMolecular Imprintingen
dc.subjectProteinen
dc.subjectNanomaterialsen
dc.titleGeneration of High-Affinity Molecularly Imprinted Nanoparticles for Protein Recognition via a Solid-Phase Synthesis Protocolen
dc.typeBook chapteren
dc.identifier.doihttps://doi.org/10.1007/978-1-4939-9869-2_11
dc.peerreviewedYesen
dc.funderEPSRC (Engineering and Physical Sciences Research Council)en
dc.projectidEP/S003339/1en
dc.cclicenceCC-BY-NCen
dc.date.acceptance2019-10-15
dc.researchinstituteLeicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)en


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