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dc.contributor.authorJin, Yannan
dc.contributor.authorGordon, Mike
dc.contributor.authorAlimbetov, Dauren
dc.contributor.authorChong, M.F.
dc.contributor.authorGeorge, T.W.
dc.contributor.authorSpencer, J.P.E.
dc.date.accessioned2019-06-12T13:41:13Z
dc.date.available2019-06-12T13:41:13Z
dc.date.issued2015-04-15
dc.identifier.citationJin, Y., Gordon, M.H., Alimbetov, D., Chong, M.F., George, T.W., Spencer, J.P.E. (2015) OC38: Introduction of plasma vitamin C and Ferric Reducing Antioxidant Power into a combined biomarker with plasma carotenoids increases the association with fruit and vegetable intake. Proceedings of the Nutrition Society, 74 (OCE1), E38.en
dc.identifier.urihttp://hira.hope.ac.uk/id/eprint/1313
dc.identifier.urihttps://www.dora.dmu.ac.uk/handle/2086/18038
dc.descriptionThe Publisher's final version can be found by following the DOI link.en
dc.description.abstractMonitoring of fruit and vegetable (F&V) intake is fraught with difficulties. Available dietary assessment methods are associated with considerable error and use of biomarkers offers an attractive alternative(1). Few studies to date have examined the use of plasma biomarkers to monitor or predict F&V intake of volunteers consuming a wide range of intake from both habitual F&V and manipulated diets. This study combined plasma vitamin C and carotenoid concentrations with Ferric Reducing Antioxidant Power (FRAP) as an integrated biomarker of F&V intake and compared the predictive powers of each single and integrated biomarker for F&V intake. Data from a randomized, controlled, dietary intervention study (FLAVURS) (n = 154) in which the test groups had observed sequential increases of 2.3, 3.2 and 4.2 portions of F&V every 6-wk across an 18-wk period was used in this study. A modified integrated plasma biomarker was devised which included plasma vitamin C, total carotenoids and FRAP values, and this gave a better correlation with F&V intake (r = 0.516, P < 0.001) than the individual biomarkers (r = 0.332, P < 0.001; r = 0.417, P < 0.001; r = 0.136, P = 0.099 respectively). Inclusion of urinary potassium concentration did not significantly improve the correlation. The modified integrated plasma biomarker more accurately predicted F&V intake to within 2 portions of the actual intake in 54.3 ± 4.9% of the population compared with plasma carotenoid concentration (48.3 ± 11.3%), although this difference did not reach statistical significance (P > 0.05). Either plasma carotenoid concentration or the integrated biomarker could be used to distinguish high and low F&V consumers.en
dc.language.isoenen
dc.publisherProceedings of the Nutrition Societyen
dc.titleIntroduction of plasma vitamin C and Ferric Reducing Antioxidant Power into a combined biomarker with plasma carotenoids increases the association with fruit and vegetable intakeen
dc.typeConferenceen
dc.identifier.doihttps://doi.org/10.1017/S0029665115000531
dc.peerreviewedYesen
dc.funderNo external funderen
dc.cclicenceCC-BY-NCen
dc.exception.reasonavailable on Liverpool Hope Uni's repositoryen
dc.researchinstituteInstitute for Allied Health Sciences Researchen
dc.exception.ref2021codes254aen


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