Influence of surface-imprinted nanoparticles on trypsin activity
Here, the modulation of enzyme activity is presented by protein‐imprinted nanoparticles produced using a solid‐phase approach. Using trypsin as target, binding of the nanoparticles to the enzyme results in its inhibition or in stabilization, depending on the orientation of the immobilized enzyme used during imprinting.
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.
Citation : Guerreiro, A., Poma, A., Karim, K., Moczko, E., Takarada, J., de Vargas-Sansalvador, I., Turner, N.W., Piletska, E., de Magalhães, C.S., Glazova, N., Serkova, A., Omelianova, A., Piletsky, S.(2014) Influence of surface-imprinted nanoparticles on trypsin activity. Advanced Healthcare Materials, 3(9), pp.1426–1429.
ISSN : 2192-2659
Research Institute : Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)
Peer Reviewed : Yes
- Leicester School of Pharmacy