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dc.contributor.authorSokunbi, M.O.en
dc.contributor.authorStaff, R.T.en
dc.contributor.authorWaiter, G.D.en
dc.contributor.authorAhearn, T.S.en
dc.contributor.authorFox, H.C.en
dc.contributor.authorDeary, I.J.en
dc.contributor.authorWhalley, L.J.en
dc.contributor.authorMurray, A.D.en
dc.date.accessioned2018-03-01T11:55:17Z
dc.date.available2018-03-01T11:55:17Z
dc.date.issued2011-08-22
dc.identifier.citationSokunbi, M.O., Staff, R.T., Waiter, G.D., Ahearn, T.S., Fox, H.C., Deary, I.J., Starr, J.M., Whalley, L.J., Murray, A.D. (2011) Inter-individual Differences in fMRI Entropy Measurements in Old Age. IEEE Transactions on Biomedical Engineering, 58(11), pp.3206 - 3214.en
dc.identifier.urihttp://hdl.handle.net/2086/15323
dc.descriptionThe file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI linken
dc.description.abstractWe investigated the association between individual differences in cognitive performance in old age and the approximate entropy (ApEn) measured from functional magnetic resonance imaging (fMRI) data acquired from 40 participants of the Aberdeen Birth Cohort 1936 (ABC1936), while undergoing a visual information processing task: inspection time (IT). Participants took a version of the Moray House Test (MHT) No. 12 at age 11, a valid measure of childhood intelligence. The same individuals completed a test of non-verbal reasoning (Raven’s Standard Progressive Matrices [RPM]) aged about 68 years. The IT, MHT and RPM scores were used as indicators of cognitive performance. Our results show that higher regional signal entropy is associated with better cognitive performance. This finding was independent of ability in childhood but not independent of current cognitive ability. ApEn is used for the first time to identify a potential source of individual differences in cognitive ability using fMRI data.en
dc.language.isoenen
dc.publisherIEEEen
dc.subjectApproximate entropy (ApEn)en
dc.subjectblood oxygen level dependent (BOLD)en
dc.subjectfunctional magnetic resonance imaging (fMRI)en
dc.subjectinspection time (IT)en
dc.subjectRaven’s matricesen
dc.subjectScottish mental surveyen
dc.titleInter-individual Differences in fMRI Entropy Measurements in Old Ageen
dc.typeArticleen
dc.identifier.doihttps://doi.org/10.1109/tbme.2011.2164793
dc.peerreviewedYesen
dc.funderThis work was supported in part by the Alzheimer Research Trust, in part by the Wellcome Trust, and in part by a SINAPSE (www.sinapse.ac.uk) studentship.en
dc.projectidN/Aen
dc.cclicenceCC-BY-NCen
dc.date.acceptance2011-07-14en
dc.exception.reasonAt the time of publication the author was not DMU staff.en


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