Time domain Dielectric Spectroscopy Study of Human Cells. II. Normal and Malignant White Blood Cells
The dielectric properties of human lymphocyte suspensions were studied by time domain dielectric spectroscopy (TDDS). Nine populations of malignant and normal lymphocytes were investigated. Analysis of the dielectric parameters of cell structural parts were performed in the framework of Maxwell^Wagner mixture formula and the double-shell model of cell. The specific capacitance of the cell membranes was estimated by the Hanai^Asami^Koisumi formula. It was shown that the dielectric permittivity, capacitance and conductivity values of cell membranes are higher for normal lymphocytes than for the malignant ones. The difference of the same parameters for normal B- and T-cells is also discussed.
open access article
Citation : Polevaya et al., (1999) Time domain Dielectric Spectroscopy Study of Human Cells. II. Normal and Malignant White Blood Cells. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1419 (2) 257-271.
Research Institute : Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)
Peer Reviewed : Yes
- Leicester School of Pharmacy