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dc.contributor.authorOgbechie, A.en
dc.contributor.authorAbioye, A. O.en
dc.contributor.authorShen, Jinsongen
dc.contributor.authorLaird, Katieen
dc.date.accessioned2017-04-28T10:31:04Z
dc.date.available2017-04-28T10:31:04Z
dc.date.issued2017-04
dc.identifier.citationOgbechie, A., Abioye, A., Shen, J. and Laird, K. (2017) Antimicrobial activity of Litsea cubeba, Rosmarinus officinalis and Citrus lemon essential oils against five skin-infection related pathogens. Trends in Natural Product Research Meeting, Lille Franceen
dc.identifier.urihttp://hdl.handle.net/2086/14122
dc.description.abstractAxillary odour, athlete’s foot, eczema and infected wounds, are all conditions that are caused by organisms such as Staphylococcus aureus, Staphylococcus epidermidis, Trichophyton rubrum, Escherichia coli and Pseudomonas aeruginosa. Antimicrobial textiles such as wound dressings may go some way in combating such diseases. It is becoming increasingly important to consider the environment when selecting consumer goods such as antimicrobial textiles, problems such as toxicity and other health hazards have led to processing of textiles by more eco-friendly methods. Thus, Essential oils (EOs) may be a natural alternative to chemical based antimicrobials1. Ten EOs were screened by the disc diffusion method against S. aureus, P. aeruginosa, E. coli, S. epidermidis and T. rubrum. The Minimum Inhibitory Concentrations (MICs), Minimum Bactericidal Concentrations (MBCs) and Fractional Inhibitory Concentrations (FICs) of Litsea cubeba (Litsea), Citrus limon (Lemon) and Rosmarinus officinalis (Rosemary) EOs were determined using the microdilution method. Litsea oil was most effective, with an average zone of inhibition (ZoI) of 47 mm, 20 mm, 53 mm, 43 mm and 90mm (complete inhibition) against S. aureus, P. aeruginosa, E. coli, S. epidermidis and T. rubrum respectively. S. aureus was the most susceptible bacterial organism, being inhibited by all EOs tested; P. aeruginosa in turn was the most resistant to the EOs. Litsea EO gave lowest MICs and MBCs against all microorganisms, with the lowest MIC and MBC observed against S. epidermidis (0.60 and 1.30 mg/ml respectively). The organisms were least susceptible to Lemon EO, with generally higher MICs and MBCs. Further investigations are underway to determine synergistic activity between the EOs and the chemical components responsible for the activity. References: 1. Kavanaugh N.L. & Ribbeck K., 2012. Selected antimicrobial essential oils eradicate Pseudomonas spp. and Staphylococcus aureus biofilms. Applied and Environmental Microbiology, 78, 4057-4061.en
dc.publisherPhytochemical Society of Europeen
dc.subjectantimicrobial activityen
dc.subjectessential oilen
dc.subjectnatural antimicrobialsen
dc.titleAntimicrobial activity of Litsea cubeba, Rosmarinus officinalis and Citrus lemon essential oils against five skin-infection related pathogensen
dc.typeConferenceen
dc.researchgroupInfectious Disease Research Groupen
dc.researchgroupInfectious Disease Research Group
dc.peerreviewedYesen
dc.funderN/Aen
dc.projectidN/Aen
dc.cclicenceCC-BY-NCen
dc.researchinstituteLeicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)en
dc.researchinstituteInstitute of Art and Designen


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