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Quantitative LC-ToF MS analyses of dried blood spots: Developing an assessment of medication adherence for heart disease patients
Introduction: Over 355 million prescriptions were dispensed for cardiovascular diseases in the UK in 20131. Half of these, costing the NHS £2.3 billion, were wasted because patients did not take their medicines as prescribed2. ...
High resolution LC-ToF mass spectrometry data used for drug monitoring in clinical applications using dried blood spot samples
Quantitative dried blood spot (DBS) analysis was used to investigate if the accurate mass capability (±2ppm m/z) of high resolution mass spectrometry (HRMS) would provide compound specificity comparable to the multiple ...