Now showing items 1-5 of 5
Quantitative LC-HRMS determination of selected cardiovascular drugs, in dried blood spots, as an indicator of adherence to medication
Dried blood spot (DBS) sampling was investigated as a means of obtaining micro-volume blood samples for the quantitative analyses of ten commonly UK prescribed cardiovascular drugs as an indicator of medication adherence. ...
Volumetric absorptive microsampling (VAMS) coupled with high-resolution, accurate-mass (HRAM) mass spectrometry as a simplified alternative to dried blood spot (DBS) analysis for therapeutic drug monitoring of cardiovascular drugs
Here, volumetric absorptive microsampling (VAMS), used for the measurement of cardiovascular drugs, is compared against conventional dried blood spot (DBS) card sampling to evaluate adherence to prescribed medication. ...
Performance of two different microsamplers for the LC-HRMS analysis of 10 cardiovascular drugs
Introduction: Evidence suggests that ˃50% of heart disease patients do not adhere to treatment. This means half of the 370 million prescriptions dispensed for cardiovascular diseases (CVD) in the UK yearly, are wasted . ...
It’s in a drop of blood – or is it?
Introduction: Over 355 million prescriptions were dispensed for heart diseases in the UK in 2013. Half of these, costing the NHS £2.3 billion, were wasted because patients did not take their medicines as prescribed . ...
Comparison of VAMS and card based microsampling with LC-HRMS analysis to assess cardiovascular drug levels
Summary: An objective means of assessing medication adherence is needed to enable patients get the maximum therapeutic benefits from their medication. A bioanalytical assay using dried blood spot (DBS) and volumetric ...