Now showing items 1-10 of 64
Quantitative dried blood spot analyses: An aid to medicine optimization for heart disease patients
Introduction: Over 355 million prescriptions were dispensed for cardiovascular diseases in the UK in 2013. Half of these, costing the NHS £2.3 billion, were wasted because patients do not take their medicines as prescribed. ...
Mass spectrometry studies of organolead compounds
Cardiovascular drug monitoring using quantitative LC-HRMS analysis of self-collected micro-volume blood samples
Background Evidence suggests that ˃50% of cardiovascular (CVD) disease patients do not adhere to treatment thus impacting on patient health, additional healthcare costs and medicines wastage. DBS microsampling combined ...
Captopril Determination in Dried Blood Spot Samples with LC-MS and LCHRMS: A Potential Method for Neonate Pharmacokinetic Studies
(OMICS Publishing Group, 2012-03-07)
The use of blood spot collection cards was investigated as a means of obtaining small volume samples for the analysis of therapeutic drugs for the purpose of neonatal pharmacokinetic studies. We describe the development ...
Quantitative LC-ToF MS analyses of dried blood spots: Developing an assessment of medication adherence for heart disease patients
Introduction: Over 355 million prescriptions were dispensed for cardiovascular diseases in the UK in 20131. Half of these, costing the NHS £2.3 billion, were wasted because patients did not take their medicines as prescribed2. ...