Now showing items 1-10 of 279
Recent advances in exosome-based nanovehicles as RNA interference therapeutic carriers
RNA interference (RNAi) therapeutics (siRNA, miRNA, etc.) represent an emerging medicinal remedy for a variety of ailments. However, their low serum stability and low cellular uptake signi cantly restrict their clinical ...
RNAi-combined nano-chemotherapeutics to tackle resistant tumors
The merger of nanotechnology and combination chemotherapy has shown notable promise in the therapy of resistant tumors. The latest scientific attention encompasses the engagement of anticancer drugs in combination with ...
Supporting underserved patients with their medicines: a patient / professional co-produced education intervention for community pharmacy staff to improve the provision and delivery of Medicine Use Reviews
(BMJ Open Access, 2016-12-09)
Introduction Community pharmacy increasingly features in global strategies to modernise the delivery of primary healthcare. Medicine Use Reviews (MURs) form part of the English Government's medicines management strategy ...
Evaluation of a care home clinical medication review service by a primary care pharmacist.
(Royal Pharmaceutical Society of Great Britain, 2012-09)
Focal points • This study evaluates a clinical medication review service for care home patients provided by a primary care pharmacist working alongside GPs. • 237 one-off clinical medication reviews were completed in 8 ...
Patients' attitudes to risk in lung cancer surgery: A qualitative study.
(Lung Cancer, 2015-11)
Lung Cancer. 2015 Nov;90(2):358-63. doi: 10.1016/j.lungcan.2015.08.014. Epub 2015 Aug 24. Patients' attitudes to risk in lung cancer surgery: A qualitative study. Powell HA1, Jones LL2, Baldwin DR3, Duffy JP4, Hubbard ...
Nociceptin/orphanin FQ (N/OFQ) modulates immunopathology and airway hyperresponsiveness representing a novel target for the treatment of asthma.
(British Pharmacological Society, 2016-03-06)
BACKGROUND AND PURPOSE: There is evidence supporting a role for the nociceptin/orphanin FQ (N/OFQ; NOP) receptor and its endogenous ligand N/OFQ in the modulation of neurogenic inflammation, airway tone and calibre. We ...
Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS
Allergen exposure may induce changes in the brainstem secondary neurons, with neural sensitization of the nucleus solitary tract (NTS), which in turn can be considered one of the causes of the airway hyperresponsiveness, ...
Randomized trial of red cell washing for the prevention of transfusion-associated organ injury in cardiac surgery.
(Oxford Academic, 2017-05-15)
BACKGROUND: Experimental studies suggest that mechanical cell washing to remove pro-inflammatory components that accumulate in the supernatant of stored donor red blood cells (RBCs) might reduce inflammation and organ ...
Radiostability of florfenicol in the solid state
(Japan Society for Analytical Chemistry, 2009)