Browsing Leicester School of Pharmacy by Subject "MbtA"
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Rational design, synthesis and preliminary biological evaluation of novel C8-linked pyrrolobenzodiazepine-5′-O-[N-(salicyl)sulfamoyl]adenosine conjugates (PBD-Sal-AMS) as anti-tubercular probes with dual mode of action. (Conference)Tuberculosis (TB), a disease caused by Mycobacterium tuberculosis, affects an estimated 10 million people worldwide, causing around 2 million human deaths yearly. The emergence of multi-drug resistant strains and lack of ...