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dc.contributor.authorGoodyer, E. N.en
dc.contributor.authorGunderson, M.en
dc.contributor.authorTateya, C.en
dc.contributor.authorTataya, T.en
dc.contributor.authorDailey, S. M.en
dc.date.accessioned2016-06-06T10:41:59Z
dc.date.available2016-06-06T10:41:59Z
dc.date.issued2016-04-17
dc.identifier.citationGoodyer, E.N., Gunderson, M.L., Tateya, C., Tateya, T. and Dailey, S.H. (2016) The Anisotropic Elasticity of the Human Vocal Fold. Journal of Otology and Rhinology, 5:2en
dc.identifier.urihttp://hdl.handle.net/2086/12122
dc.descriptionA review of the work carried out jointly with UKE Hamburg, which demostrated the anisotropic nature of the human vocal folds. This additional work presents collagen and elastin stains to support that research. APC paid for Open Accessen
dc.description.abstractObjective: To verify the anisotropic nature of the vocal folds by reproducing an experiment led by Rholfs that measured vocal fold elasticity in the transverse and longitudinal directions. To present a physiological explanation of the measured phenomena using immunochemical results. Methods: 6 cadaveric human excised larynges were hemi-sectioned in the mid-sagittal plane exposing the vocal folds, and orthogonal measurements of tension made at 3 equally spaced points. Immunohistochemistry carried out by Ichiro Tateya was used to visualise collagens and elastins in the deep layer of the lamina propria. Results: The LSR results indicate that the measured elasticity of the vocal folds are highly anisotropic. The immunohistochemistry results show that there is a strong alignment of collagens and elastins along the longitudinal axis of human vocal folds. Conclusion: The measured anisotropic behaviour is due to the alignment of collagens & elastins in the lamina propriaen
dc.language.isoenen
dc.publisherSciTechnolen
dc.subjectvocal foldsen
dc.subjecttissue elasticityen
dc.subjectanisotropicen
dc.titleThe Anisotropic Elasticity of the Human Vocal Folden
dc.typeArticleen
dc.identifier.doihttp://dx.doi.org/10.4172/2324-8785.1000275
dc.researchgroupDIGITSen
dc.peerreviewedYesen
dc.funderEPSRC (Engineering and Physical Sciences Research Council)en
dc.projectidEP/N018931/1en
dc.cclicenceCC BYen
dc.date.acceptance2016-04-12en
dc.exception.reasonAPC paid but no OA version on journal websiteen


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