Dietary Flavonoids and The Prevention of Degenerative Diseases

De Montfort University Open Research Archive

Show simple item record Söhretoglu, Didem en Arroo, R. R. J. en 2015-01-14T10:25:37Z 2015-01-14T10:25:37Z 2015
dc.identifier.citation Söhretoglu, D. and Arroo, R.R.J. (2015) Dietary Flavonoids and The Prevention of Degenerative Diseases. In: Govil, J.N. and Pathak, M. eds. Recent Progress in Medicinal Plants Volume 40 - Flavonoids and Antioxidants. Studium Press LLC, U.S.A. pp.331 - 351 en
dc.identifier.isbn 1626990778
dc.description Joint project with Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, Sıhhiye, 06100, Ankara, Turkey en
dc.description.abstract Flavonoids are a group of compounds commonly found in fruits, vegetables, cereals, chocolate, and beverages such as tea, coffee and wine. Epidemiological studies have unambiguously shown that there is a positive correlation between regular fruit and vegetable intake and a lower occurrence of a variety of degenerative diseases. It is widely assumed that particularly the dietary flavonoids in fruits and vegetables play a key role in exerting beneficial effects on coronary heart disease, stroke, Parkinson's Disease, Alzheimer's disease etc. Traditionally, the positive effects of flavonoids were attributed to their antioxidant actions. Although flavonoids have been identified as powerful antioxidants in vitro, their ability to act as antioxidants in vivo is limited by extensive biotransformation and conjugation which occur during their absorption from the gastrointestinal tract in the liver and finally in cells. Thus, the beneficial effects of flavonoids on prevention of degenerative diseases go far beyond what may be expected of an antioxidant effect alone; other mechanisms must be involved. Consequently, more research needs to be done into the correlation of effects of flavonoids on degenerative diseases and their possible mechanisms of action. en
dc.language.iso en en
dc.publisher Studium Press LLC, U.S.A en
dc.relation.ispartofseries Recent Progress in Medicinal Plants;40
dc.subject Antioxidant en
dc.subject Stroke en
dc.subject Parkinson en
dc.subject Alzheimer en
dc.title Dietary Flavonoids and The Prevention of Degenerative Diseases en
dc.type Book chapter en
dc.peerreviewed Yes en
dc.explorer.multimedia No en
dc.funder De Montfort University en
dc.projectid Natural Products Research en

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