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    Browsing by Author "Wang, Ke"

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      • Cocrystallisation of Daidzein with pyridine-derived molecules: Screening, structure determination and characterisation 

        Bolus, Linzie; Wang, Ke; Pask, Christopher; Lai, Xiaojun; Li, M. (Article)
        Daidzein (7,4' -dihydroxyisoflavone, DAI) is an isoflavone found in soybeans and Pueraria. DAI has potential therapeutic benefits on cancer and osteoporosis yet has quite low solubility, limiting its use. Herein a cocrystal ...
      • In Vitro Dissolution Studies of Immediate Release and Extended Release Formulation using Flow-through Cell Apparatus 4. Dissolution technologies 

        Qiu, S.; Wang, Ke; Li, M. (Article)
        The aims of this study were to evaluate the dissolution performance of solid dosage forms using the open and closed modes of the FTC Apparatus 4 under different flow rates and provide examples to demonstrate the advantages ...
      • Insight into Flufenamic Acid Cocrystal Dissolution in the Presence of a Polymer in Solution: from Single Crystal to Powder Dissolution 

        Guo, Minshan; Wang, Ke; Qiao, Ning; Fabian, Laszlo; Sadiq, Ghazala; Li, M. (Article)
        Effects of three polymers, polyethylene glycol (PEG), polyvinylpyrrolidone (PVP), and copolymer of vinylpyrrolidone/vinyl acetate (PVP-VA), on the dissolution behavior of the cocrystals of flufenamic acid with theophylline ...
      • Investigating Permeation Behavior of Flufenamic Acid Cocrystals Using a Dissolution and Permeation System 

        Guo, Minshan; Wang, Ke; Qiao, Ning; Yardley, Vanessa; Li, M. (Article)
      • Investigating the Influence of Polymers on Supersaturated Flufenamic Acid Cocrystal Solutions 

        Guo, Minshan; Wang, Ke; Hamill, Noel Anthony; Lorimer, Keith; Li, M. (Article)
      • Investigation of the Effect of Hydroxypropyl Methylcellulose on the Phase Transformation and Release Profiles of Carbamazepine-Nicotinamide Cocrystal 

        Li, M.; Qiu, Shi; Wang, Ke; Lai, Xiaojun; Rehan, Mohammad (Article)
        Purpose The aim of this work was to investigate the influence of hydroxypropyl methylcellulose (HPMC) on the phase transformation and release profile of carbamazepine-nicotinamide (CBZ-NIC) cocrystal in solution and in ...
      • Role of polymers in solution and tablet-based carbamazepine cocrystal formulations 

        Qiu, Shi; Lai, Jumin; Guo, Minshan; Wang, Ke; Lai, Xiaojun; Desai, Unmesh; Juma, Nazmin; Li, M. (Article)
      • Understanding the effects of a polymer on the surface dissolution of pharmaceutical cocrystals using combined experimental and molecular dynamics simulation approaches 

        Li, M.; Kirubakaran, P.; Wang, Ke; Rosbottom, I.; Cross, R. B. M. (Article)
        The molecular interactions between the surfaces of cocrystals [i.e., flufenamic acid and theophylline (FFA-TP), flufenamic acid and nicotinamide (FFA-NIC), and carbamazepine and nicotinamide (CBZ-NIC)] and the polymers ...

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