Browsing by Author "Styles, Jerry"
Now showing items 1-3 of 3
-
Effects of Estrogen Receptor Modulators on Uterine Pathology and Gene Expression.
Gray, Douglas T.; Greaves, Peter; Styles, Jerry; White, Ian (Conference)Tamoxifen, a selective estrogen receptor modulator (SERM), is an effective treatment for breast cancers. In the CD-1 mouse model, neonatal oral dosing with tamoxifen leads to the development of adenomyosis. Subcutaneous ... -
Pathology and Gene Expression in the Uteri of Mice Dosed with Oestradiol and Tamoxifen.
Gray, Douglas T.; Greaves, Peter; Styles, Jerry; White, Ian (Conference)There is a marked difference in the development of uterine pathologies following administration of tamoxifen to neonatal mice by different routes. Oral dosing causes adenomyosis while subcutaneous administration results ...