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    Browsing by Author "Styles, Jerry"

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      • Effects of Estrogen Receptor Modulators on Uterine Pathology and Gene Expression. 

        Gray, Douglas T.; Greaves, Peter; Styles, Jerry; White, Ian (Conference)
        Tamoxifen, a selective estrogen receptor modulator (SERM), is an effective treatment for breast cancers. In the CD-1 mouse model, neonatal oral dosing with tamoxifen leads to the development of adenomyosis. Subcutaneous ...
      • Neonatal tamoxifen treatment of mice leads to adenomyosis but not uterine cancer. 

        Gray, Douglas T.; Green, A.; White, Ian; Styles, Jerry; Edwards, Richard; Smith, A.; Gant, T.; Greaves, Peter; Al-Azzawi, Farook (Article)
      • Pathology and Gene Expression in the Uteri of Mice Dosed with Oestradiol and Tamoxifen. 

        Gray, Douglas T.; Greaves, Peter; Styles, Jerry; White, Ian (Conference)
        There is a marked difference in the development of uterine pathologies following administration of tamoxifen to neonatal mice by different routes. Oral dosing causes adenomyosis while subcutaneous administration results ...

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