Browsing by Author "Smith, Geoff"
Now showing items 1-20 of 79
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3D non-invasive inspection of the skin lesions by close-range and low-cost photogrammetric techniques
Orun, A.; Goodyer, E. N.; Smith, Geoff (Article)In dermatology, one of the most common causes of skin abnormality is an unusual change in skin lesion structure which may exhibit very subtle physical deformation of its 3D shape. However the geometrical sensitivity of ... -
The application of dual-electrode through vial impedance spectroscopy for the determination of ice interface temperatures, primary drying rate and vial heat transfer coefficient in lyophilization process development
Smith, Geoff; Jeeraruangrattana, Yowwares; Ermolina, I. (Article)Through vial impedance spectroscopy (TVIS) is a product non-invasive process analytical technology which exploits the frequency dependence of the complex impedance spectrum of a composite object (i.e. the freeze-drying ... -
Correlation between molecular dynamics and physical stability of two milled anhydrous sugars: lactose and sucrose
Smith, Geoff; Hussain, Amjad; Bukhari, Nadeem Irfan; Ermolina, I. (Article)The process of milling often results in amorphization and the physical stability of amorphous phase is linked with its molecular dynamics. This study focuses on a propensity of two disaccharides (lactose and sucrose) to ... -
Determination of ice interface temperature, sublimation rate and the dried product resistance, and its application in the assessment of microcollapse using through-vial impedance spectroscopy
Smith, Geoff; Jeeraruangrattana, Yowwares; Polygalov, E.; Ermolina, I. (Article)Through-vial impedance spectroscopy (TVIS) is a new approach for characterizing product attributes during freeze-drying process development. In this study, a pair of copper foil electrodes was attached to the external ...