Browsing by Author "Owen, Lucy"
Now showing items 1-15 of 15
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Antimicrobial Activity of Ternary Essential Oil Mixtures in Topical Cosmetic Preparations Against Acne Vulgaris-Associated Bacteria.
Owen, Lucy; Grootveld, M.; Arroo, R. R. J.; Ruiz-Rodado, Victor; Price, Penny; Laird, Katie (Conference)Acne vulgaris is a chronic skin condition associated with overgrowth of Propionibacterium acnes and Staphylococcus epidermidis. Antibiotics are commonly prescribed to control acne; however, resistance has emerged, indicating ... -
Characterisation and screening of antimicrobial essential oil components against clinically important antibiotic-resistant bacteria using thin layer chromatography-direct bioautography hyphenated with GC-MS, LC-MS and NMR.
Owen, Lucy; White, A.; Laird, Katie (Article)Introduction: The antimicrobial activity of many Essential Oils (EOs) is well established, indicating that EOs may be a source of compounds for antimicrobial drug development. Thin Layer Chromatography-Direct Bioautography ... -
Dual-Function Antimicrobial Laundry Supplement and Textile Coating for the Decontamination of Healthcare Laundry
Owen, Lucy; Laird, Katie (Conference)Background: In the UK nurses’ uniforms are domestically laundered, posing a threat of cross contamination of healthcare-associated infections. The UK Department of Health recommends washing uniforms at 60ºC, however nurses ... -
The Effect of Low Temperature Laundering and Detergents on the Survival of Escherichia coli and Staphylococcus aureus on Textiles Used in Healthcare Uniforms
Riley, Kate; Williams, J.; Davis, A.; Shen, Jinsong; Laird, Katie; Owen, Lucy (Article)Aims: To determine the survival of Escherichia coli and Staphylococcus aureus on cotton and polyester and the effectiveness of low temperature laundering and detergents on the removal of microorganism from healthcare ... -
From formulation to in vivo model: A comprehensive study of a synergistic relationship between vancomycin, carvacrol and cuminaldehyde against Enterococcus faecium
Owen, Lucy; Webb, Joseph P.; Green, Jeffrey; Smith, Laura J.; Laird, Katie (Article)Vancomycin Resistant Enterococcus faecium (VRE) has become endemic in healthcare settings, reducing treatment options for enterococcal infections. New antimicrobials for VRE infections are a high priority, but the development ... -
A multi-faceted approach to determining the efficacy of metal and metal oxide nanoparticles against bacterial biofilms
Tejpal, Jyoti; Cross, R. B. M.; Owen, Lucy; Paul, Shashi; Jenkins, R. O.; Armitage, David; Laird, Katie (Article)Antibacterial efficacy of nanoscale silver, copper (II) oxide and zinc oxide were assessed against Pseudomonas aeruginosa and Staphylococcus aureus biofilms in solution and on surfaces. Using a Center for Disease Control ... -
A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria.
Laird, Katie; Owen, Lucy; Ruiz-Rodado, Victor; Price, Penny; Grootveld, M.; Arroo, R. R. J. (Article)Acne vulgaris, a chronic condition associated with overgrowth of Propionibacterium acnes and Staphylococcus epidermidis, is commonly treated with antibiotics. However, the emergence of antibiotic resistance has resulted ... -
The role of protective clothing in healthcare and its decontamination
Laird, Katie; Owen, Lucy (Book chapter)Healthcare-associated infections (HAIs) are a significant cause of morbidity and mortality and pose a major economic burden. Infection control is therefore important in healthcare environments to minimize the transmission ... -
Structure-activity modelling of essential oils, their components, and key molecular parameters and descriptors
Laird, Katie; Owen, Lucy; Wilson, Philippe B. (Article)Many essential oil components are known to possess broad spectrum antimicrobial activity, including against antibiotic resistant bacteria. These compounds may be a useful source of new and novel antimicrobials. However, ... -
Synchronous application of antibiotics and essential oils: dual mechanisms of action as a potential solution to antibiotic resistance
Owen, Lucy; Laird, Katie (Article)Antibiotic resistance has increased dramatically in recent years, yet the antibiotic pipeline has stalled. New therapies are therefore needed to continue treating antibiotic resistant infections. One potential strategy ... -
Synergistic Combinations of Antibiotics with Cumin, Oregano and Rosewood Oils as a Strategy to Preserve the Antibiotic Repertoire.
Owen, Lucy; Laird, Katie (Article)Background: Formulations employing synergistic combinations of antibiotics with Essential Oils (EOs) could help to preserve the antibiotic repertoire by improving their activity against resistant bacteria. Objective: This ... -
Transcriptional response of vancomycin resistant Enterococcus faecium to a synergistic antibiotic-essential oil combination: A strategy to preserve the current antibiotic repertoire?
Owen, Lucy; Webb, Joseph P.; Green, Jeffrey; Smith, Laura J.; Laird, Katie (Conference)Background: New antimicrobials to treat Vancomycin Resistant Enterococcus faecium (VRE) infections are considered a high priority. Essential oil compounds have been shown to interact synergistically with antibiotics, and ...