Generation of multi-layered structures for biomedical applications using a novel tri-needle co-axial device and electrohydrodynamic flow
In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare doublelayered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.
Citation : Ahmad, Z. et al. (2008) Generation of multi-layered structures for biomedical applications using a novel tri-needle co-axial device and electrohydrodynamic flow. Journal of the Royal Society Interface, 5 (27). pp. 1255-1261
Research Group : Pharmaceutical Technologies
Research Institute : Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)
Peer Reviewed : Yes
- Leicester School of Pharmacy