Analysis of powder caking in multicomponent powders using atomic force microscopy to examine particle properties.

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dc.contributor.author Prime, Dominic
dc.contributor.author Leaper, Mark C.
dc.contributor.author Rielly, Christopher D.
dc.contributor.author Jones, James R.
dc.contributor.author Stapley, Andrew
dc.date.accessioned 2011-04-14T14:03:18Z
dc.date.available 2011-04-14T14:03:18Z
dc.date.issued 2011-01
dc.identifier.citation Prime, D.C., et al., (2011) Analysis of Powder Caking in Multicomponent Powders Using Atomic Force Microscopy to Examine Particle Properties. Chemical Engineering and Technology, 34 (1) pp. 98-102. en
dc.identifier.issn 1521-4125
dc.identifier.uri http://hdl.handle.net/2086/4884
dc.description.abstract Atomic force microscopy has been used to study the surface properties of model spray dried powders. Phase imaging, nanoindentation and force modulation microscopy have differentiated between the different surface material properties of the particles, revealing a regular dispersion of soft, oil rich areas distributed across the particles' surface. Humidity and temperature cycling effects on the caking behavior of the particles have also been investigated, with significant morphology changes and onset of caking found to occur within relatively short periods of time. en
dc.language.iso en en
dc.publisher Wiley en
dc.subject Atomic Force Microscopy en
dc.subject particle en
dc.subject caking en
dc.title Analysis of powder caking in multicomponent powders using atomic force microscopy to examine particle properties. en
dc.type Article en
dc.identifier.doi http://dx.doi.org/10.1002/ceat.201000211
dc.researchgroup Pharmaceutical Technologies
dc.peerreviewed Yes en


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