Developing an alternative UK industrial crop Artemisia annua, for the extraction of artemisinin to treat multi-drug resistant malaria.

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dc.contributor.author Smith, L. M. J.
dc.contributor.author Bentley, S.
dc.contributor.author Jones, H.
dc.contributor.author Burns, C.
dc.contributor.author Arroo, R. R. J.
dc.contributor.author Woolley, J. G.
dc.date.accessioned 2010-09-22T13:20:08Z
dc.date.available 2010-09-22T13:20:08Z
dc.date.issued 2010
dc.identifier.citation Smith, L.M.J. et al. (2010) Developing an alternative UK industrial crop Artemisia annua, for the extraction of artemisinin to treat multi-drug resistant malaria. Aspects of Applied Biology 101. Non Food Uses of Crops, pp. 99-106 en
dc.identifier.issn 0265-1491
dc.identifier.uri http://hdl.handle.net/2086/4030
dc.description.abstract Over the last 5 years, new Artemisia annua lines have been produced with increased artemisinin levels, where the artemisinin yield (expressed as percentage artemisinin, by weight in harvested dried leaves) increased from 1.2-2.2%. In addition to these genetic improvements, agronomic techniques that improve the overall yield of artemisinin and increase seed yield have also been achieved. Techniques for accurate measurement of artemisinin have been considered and the presence of additional compounds, which could impact on accurate measurement of the active pharmaceutical ingredient. The genetic and agronomic improvements reported here suggest that artemisinin yields in commercial production could be raised to 60 kg ha-1, a figure that compares well with the 2010 industry average of 24 kg ha-1. en
dc.language.iso en en
dc.publisher The Association of Applied Biologists en
dc.title Developing an alternative UK industrial crop Artemisia annua, for the extraction of artemisinin to treat multi-drug resistant malaria. en
dc.type Article en
dc.researchgroup Chemistry for Health
dc.peerreviewed Yes en


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