• Login
    View Item 
    •   DORA Home
    • Faculty of Health and Life Sciences
    • School of Allied Health Sciences
    • View Item
    •   DORA Home
    • Faculty of Health and Life Sciences
    • School of Allied Health Sciences
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Introduction of plasma vitamin C and Ferric Reducing Antioxidant Power into a combined biomarker with plasma carotenoids increases the association with fruit and vegetable intake

    Thumbnail
    Date
    2015-04-15
    Author
    Jin, Yannan;
    Gordon, Mike;
    Alimbetov, Dauren;
    Chong, M.F.;
    George, T.W.;
    Spencer, J.P.E.
    Metadata
    Show attachments and full item record
    Abstract
    Monitoring of fruit and vegetable (F&V) intake is fraught with difficulties. Available dietary assessment methods are associated with considerable error and use of biomarkers offers an attractive alternative(1). Few studies to date have examined the use of plasma biomarkers to monitor or predict F&V intake of volunteers consuming a wide range of intake from both habitual F&V and manipulated diets. This study combined plasma vitamin C and carotenoid concentrations with Ferric Reducing Antioxidant Power (FRAP) as an integrated biomarker of F&V intake and compared the predictive powers of each single and integrated biomarker for F&V intake. Data from a randomized, controlled, dietary intervention study (FLAVURS) (n = 154) in which the test groups had observed sequential increases of 2.3, 3.2 and 4.2 portions of F&V every 6-wk across an 18-wk period was used in this study. A modified integrated plasma biomarker was devised which included plasma vitamin C, total carotenoids and FRAP values, and this gave a better correlation with F&V intake (r = 0.516, P < 0.001) than the individual biomarkers (r = 0.332, P < 0.001; r = 0.417, P < 0.001; r = 0.136, P = 0.099 respectively). Inclusion of urinary potassium concentration did not significantly improve the correlation. The modified integrated plasma biomarker more accurately predicted F&V intake to within 2 portions of the actual intake in 54.3 ± 4.9% of the population compared with plasma carotenoid concentration (48.3 ± 11.3%), although this difference did not reach statistical significance (P > 0.05). Either plasma carotenoid concentration or the integrated biomarker could be used to distinguish high and low F&V consumers.
    Description
    The Publisher's final version can be found by following the DOI link.
    Citation : Jin, Y., Gordon, M.H., Alimbetov, D., Chong, M.F., George, T.W., Spencer, J.P.E. (2015) OC38: Introduction of plasma vitamin C and Ferric Reducing Antioxidant Power into a combined biomarker with plasma carotenoids increases the association with fruit and vegetable intake. Proceedings of the Nutrition Society, 74 (OCE1), E38.
    URI
    http://hira.hope.ac.uk/id/eprint/1313
    https://www.dora.dmu.ac.uk/handle/2086/18038
    DOI
    https://doi.org/10.1017/S0029665115000531
    Research Institute : Institute for Allied Health Sciences Research
    Peer Reviewed : Yes
    Collections
    • School of Allied Health Sciences [1420]

    Submission Guide | Reporting Guide | Reporting Tool | DMU Open Access Libguide | Take Down Policy | Connect with DORA
    DMU LIbrary
     

     

    Browse

    All of DORACommunities & CollectionsAuthorsTitlesSubjects/KeywordsResearch InstituteBy Publication DateBy Submission DateThis CollectionAuthorsTitlesSubjects/KeywordsResearch InstituteBy Publication DateBy Submission Date

    My Account

    Login

    Submission Guide | Reporting Guide | Reporting Tool | DMU Open Access Libguide | Take Down Policy | Connect with DORA
    DMU LIbrary