Dielectric relaxation measurements on 12 kbp plasmid DNA
The dielectric properties of 12 kbp plasmid DNA have been measured as a function of temperature in the range 5 degrees C to 40 degrees C. Time domain reflectometry was used to obtain dielectric data over the frequency range from 200 kHz to 3 GHz. Values of the frequency dependent polarisability per DNA macromolecule have been determined from the measurements. Possible mechanisms that could account for the dielectric dispersion are also discussed, in particular the counterion fluctuation model of Manning-Mandel-Oosawa.
Citation : Bakewell, D.J. et al. (2000) Dielectric relaxation measurements on 12 kbp plasmid DNA. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1493 (1-2), pp. 151-158
Research Institute : Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)
Peer Reviewed : Yes
- Leicester School of Pharmacy