CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G(0)/G(1) inhibiting pRB phosphorylation.

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CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G(0)/G(1) inhibiting pRB phosphorylation.

Chaudhuri, B. ; Aubry, C. ; Mahale, S. ; Wilson, A. J. ; Jenkins, Paul R. ; Maréchal, Jean-Didier ; Sutcliffe, Michael J.
Subject: RAE 2008, UoA 13 Pharmacy
Citation: Mahale, S. et al (2006) CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G(0)/G(1) inhibiting pRB phosphorylation. Bioorganic & Medicinal Chemistry Letters, 16 (16), pp. 4272-4278.
URI: http://hdl.handle.net/2086/1334
DOI: http://dx.doi.org/10.1016/j.bmcl.2006.05.065
ISBN: 0960-894X
Research Group: Chemistry for Health
Date: 2006-06-05

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