Browsing Leicester School of Pharmacy by Subject "natural products"
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CYP1-mediated metabolism of dietary flavonoids enhances their toxicity in breast cancer cells.
(Conference)Among the different mechanisms proposed to explain the toxic effects of dietary flavonoids towards cancerous cells, substratelike interactions with cytochrome P450 CYP1 enzymes have recently been explored. In the present ... -
The Methoxylated Flavones Eupatorin and Cirsiliol Induce CYP1 Enzyme Expression in MCF7 Cells.
(Article)Flavonoids have often been associated with cancer prevention and activity of the human cytochrome P450 enzymes CYP1A1 and CYP1B1 with the occurrence of cancer. The flavones eupatorin (1) and cirsiliol (2) enhanced CYP1 ... -
Plant resources of tropical Africa 11(1) – Medicinal Plants 1.
(Book)PROTA 11 deals with the medicinal plants of Tropical Africa. Because the group is very large, it will be subdivided into 4 volumes. In PROTA 11(1) 894 'primary use' medicinal plants, belonging to a selection of 26 botanical ... -
Untapping the potential of terpenoid natural products as antimicrobial and anti-cancer probes
(Conference)Atractylis gummifera L. (Asteraceae) is a thistle that grows throughout the Mediterranean region and is widely known for its acute toxicity. The plant rhizome contains the active principle atractyloside (1), which consists ...