Browsing Leicester School of Pharmacy by Title
Now showing items 472-491 of 1197
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First detection of the nonsteroidal anti-inflammatory drug flunixin in sheep’s wool.
(Article)Exposure to the nonsteroidal anti-inflammatory drug (NSAID) diclofenac resulted in the near extinction of three species of Gyps vultures on the Indian subcontinent. Other NSAIDs present in the environment, including flunixin, ... -
The flammability of textiles when contaminated with paraffin base products
(Article)Several fire related deaths have been reported and linked with the use of paraffin base skin creams/emollients. However, no scientific research has been published on the flammability of textiles when contaminated with such ... -
Flavones as tyrosinase inhibitors: kinetic studies in vitro and in silico.
(Article)Introduction – Tyrosinase is a multifunctional copper-containing oxidase enzyme that catalyzes the first steps in the formation of melanin pigments. Identification of tyrosinase inhibitors is of value for applications in ... -
Flavonoids and Their Metabolites: Prevention in Cardiovascular Diseases and Diabetes.
(Article)Abstract: The occurrence of atherosclerosis and diabetes is expanding rapidly worldwide. These two metabolic disorders often co-occur, and are part of what is often referred to as the metabolic syndrome. In order to determine ... -
Flavonols with a catechol or pyrogallol substitution pattern on ring B readily form stable dimers in phosphate buffered saline at four degrees Celsius.
(Article)Phosphate buffered saline (PBS) is a buffer commonly used in biological research. The stability of a series of flavonoids, i.e. myricetin, kaempferol, baicalein, luteolin and quercetin in PBS was assessed. Apigenin proved ... -
A focus on PAT in freeze-drying
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Follow-up of natural products isolation.
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Formulation studies on ibuprofen sodium–cationic dextran conjugate: effect on tableting and dissolution characteristics of ibuprofen
(Article)The effect of electrostatic interaction between ibuprofen sodium (IbS) and cationic diethylaminoethyl dextran (Ddex), on the tableting properties and ibuprofen release from the conjugate tablet was investigated. Ibuprofen ... -
Formulations for modulation of protein release from large-size PLGA microparticles for tissue engineering
(Article)In this study we present an approach to pre-program lysozyme release from large size (100–300 μm) poly(DLlactic acid-co-glycolic acid) (PLGA) microparticles. This approach involved blending in-house synthesized triblock ... -
From copper to court: translation from the research laboratory to the practitioner of a new methodology for revealing latent fingermarks on metal surfaces
(Conference)There has been a renaissance in the innovation of physicochemical methods for the visualisation of latent fingermarks, but the challenge is their translation into the operational context. The situation is highlighted by ... -
From copper to court: translation from the research laboratory to the practitioner of a new methodology for revealing latent fingermarks on metal surfaces.
(Conference)There has been a renaissance in the innovation of physicochemical methods for the visualisation of latent fingermarks, but the challenge is their translation into the operational context. The ... -
From formulation to in vivo model: A comprehensive study of a synergistic relationship between vancomycin, carvacrol and cuminaldehyde against Enterococcus faecium
(Article)Vancomycin Resistant Enterococcus faecium (VRE) has become endemic in healthcare settings, reducing treatment options for enterococcal infections. New antimicrobials for VRE infections are a high priority, but the development ...