Browsing Leicester School of Pharmacy by Title
Now showing items 332-351 of 1196
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Domestic laundering of nurses uniforms: what are the risks
(Article)With rises in healthcare-acquired infections (HCAIs) and antibiotic resistance, understanding transmission routes of bacteria is paramount. One possible route is nurses’ uniforms, which they wash at home. A study found ... -
The dopaminergic stabilizer pridopidine increases neuronal activity of pyramidal neurons in the prefrontal cortex
(Article)The dopaminergic stabilizer pridopidine demonstrates state-dependent effects on locomotor activity, counteracting both hypo- and hyperactivity in rats. Pridopidine has been shown to display both functional dopamine D2 ... -
Dried Blood Spot (DBS) Analysis for Healthcare Applications
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Dried blood spot (DBS) analysis for healthcare applications.
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Dried blood spot analysis to assess medication adherence and to inform personalization of treatment
(Article)Little research using dried blood spot samples to assess adherence to medication has been reported. The World Health Organisation estimates that only half of the patients in the developed world take their medication as ... -
Dried blood spot analysis to improve paediatric medication.
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Dried blood spot sampling with LC-MS analysis for routine therapeutic caffeine monitoring in neonates
(Article)A liquid chromatography–mass spectrometry (LC-MS) method was developed and validated for the determination of therapeutic levels of caffeine in dried blood spot (DBS) samples. Caffeine is used in the treatment of Apnoea ... -
Drug Salt Formation via Mechanochemistry: The Case Study of Vincamine
(Article)In the present research a salt of vincamine, a poorly bioavailable indole alkaloid derived from the leaves of Vinca minor L., was synthesized in the solid state by means of a mechanochemical process employing citric ... -
Drugs of abuse in drinking water - a review of current detection methods, occurrence, elimination, and health risks.
(Article)This review focuses on the drugs of abuse in drinking water, as their presence is of increasing global concern and trace levels of these compounds have previously been detected. Even though these levels are not toxic with ... -
Dual Rotation Centrifugal Electrospinning: A Novel Approach to Engineer Multi-Directional and Layered Fiber Composite Matrices
(Article)In this study, a dual rotation centrifugal electrospinning system (DRCES) is designed, developed and used to prepare medicated fabrics. Through simultaneous rotation of both spinneret and collector; multi-directional blended ... -
A dual-application poly (dl-lactic-co-glycolic) acid (PLGA)-chitosan composite scaffold for potential use in bone tissue engineering
(Article)The development of patient-friendly alternatives to bone-graft procedures is the driving force for new frontiers in bone tissue engineering. Poly (dl-lactic-co-glycolic acid) (PLGA) and chitosan are well-studied and ... -
Dual-Function Antimicrobial Laundry Supplement and Textile Coating for the Decontamination of Healthcare Laundry
(Conference)Background: In the UK nurses’ uniforms are domestically laundered, posing a threat of cross contamination of healthcare-associated infections. The UK Department of Health recommends washing uniforms at 60ºC, however nurses ... -
The dynamic behavior of myoglobin molecules in solution.
(Conference)