Browsing Leicester School of Pharmacy by Title
Now showing items 355-374 of 1197
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(E)-3-(3,4,5-Trimethoxyphenyl)-1-(pyridin-4-yl)prop-2-en-1-one, a heterocyclic chalconeis a potent and selectiveCYP1A1 inhibitor and cancerchemopreventative agent
(Article)The overexpression of CYP1 family of enzymes is reported to be associated with development of human carcinomas. It has been well reported that CYP1A1 specific inhibitors prevents carcinogenesis. Herein, thirteen pyridine-4-yl ... -
Educational and support needs of hospital prescribers on cardiology and respiratory wards
(Conference)Educational and support needs of hospital prescribers on cardiology and respiratory wards Abstract: (Please refer to instructions to authors and example abstract) Focal Points • This study explores the personal ... -
Effect of acidic and basic pH on Thioflavin T absorbance and fluorescence
(Article)Thioflavin T (ThT) is a fluorescent dye able to enhance significantly its fluorescence quantum yield upon binding to protein amyloids. ThT assay is widely used to detect and quantify amyloids in a variety of conditions, ... -
Effect of antidepressant drugs on the brain sphingolipid system
(Article)Background: Major depression is a common mood disorder and the central sphingolipid system has been identified as a possible drug target of this condition. Here we investigated the action of antidepressant drugs on ... -
Effect of arginine on the aggregation of protein in freeze-dried formulations containing sugars and polyol. 1. Formulation development
(Article)L-arginine was introduced into protein-based freeze-dried formulations to study the ability of arginine to reduce / prevent from protein aggregation during manufacturing, storage and reconstitution of lyophilized protein-based ... -
Effect of Arginine on the Aggregation of Protein in Freeze-Dried Formulations Containing Sugars and Polyol: II. BSA Reconstitution and Aggregation
(Article)The current paper continues our study on the ability of L-arginine to prevent/reduce the aggregation of proteins that results from the various stresses during the lyophilisation and/or storage of lyophilized protein-based ... -
Effect of carrier solvent in 1,2-indanedione formulation on the development of fingermarks on porous substrates
(Article)As an important technique for the detection of fingermarks on porous surfaces, 1,2-indanedione is widely used due to its excellent detection performance. In order to optimize the effectiveness of 1,2-indanedione, several ... -
The effect of cyanoacrylate fuming on subsequent protein stain enhancement of fingermarks in blood
(Article)This study investigates the effect of cyanoacrylate (CA) fuming, at atmospheric and vacuum conditions, on subsequent protein stain (acid violet 17) enhancement of fingermarks in blood. Fingermark depletions in blood were ... -
The Effect of Low Temperature Laundering and Detergents on the Survival of Escherichia coli and Staphylococcus aureus on Textiles Used in Healthcare Uniforms
(Article)Aims: To determine the survival of Escherichia coli and Staphylococcus aureus on cotton and polyester and the effectiveness of low temperature laundering and detergents on the removal of microorganism from healthcare ... -
The effect of mark enhancement techniques on the presumptive and confirmatory tests for blood
(Article)An investigation into the effects of physical and chemical enhancement on subsequent presumptive and confirmatory tests for human blood is presented. Human blood was deposited onto porous (white 80gsm paper and brown ... -
The effect of mark enhancement techniques on the subsequent detection of saliva
(Article)There appears to be a limited but growing body of research on the sequential analysis/treatment of multiple types of evidence. The development of an integrated forensic approach is necessary to maximise evidence recovery ... -
The effect of mark enhancement techniques on the subsequent detection of semen/spermatozoa
(Article)Fingermarks, footwear marks, blood and semen are amongst the most commonly encountered types of evidence at crime scenes. Previous work has extensively investigated fingermark and blood enhancement techniques and a sequence ... -
The effect of paint type on the development of latent fingermarks on walls
(Article)Despite recent advances in DNA technology, fingermark evidence remains a fundamental method of ascertaining an individual’s identity. Latent fingermarks are the commonest type of fingermark encountered at crime scenes. The ... -
Effect of penetration enhancers on the dynamic behavior of phosphatidylcholine headgroups in liposomes
(Article)The results of a time-domain dielectric spectroscopy (TDDS) study of the effect of two skin penetration modulators on phosphatidylcholine (PC) bilayer vesicles are presented. The complex dielectric permittivity spectra of ...