Browsing Leicester School of Pharmacy by Title

Benchtop NMR Spectroscopy and Spectral Analysis of the cis- and trans-Stilbene Products of the Wittig Reaction

Edgar, Mark; Percival, Benita; Gibson, Miles; Masania, Jinit; Beresford, Ken; Wilson, Philippe B.; Grootveld, M. (Article)

Benchtop NMR spectrometers are now becoming more widely employed in university teaching laboratories. These low-field instruments are increasingly used in reaction monitoring and product purity applications. NMR spectra ...

Beyond the Pale Horse - The Application and Impact of a Project Based Approach to a Challenging Module

Brawn, R. J.; Johnston, Emma (Conference)

Problem-Based learning (PBL) is a form of Enquiry-Based learning in which learning is focussed around an often complex and ill-defined problem, scenario or situation. Students typically work as part of a team; developing ...

Bi-phasic change in BDNF gene expression following antidepressant drug treatment

Zetterstrom, T. S. C.; Coppell, A. L.; Pei, Q. (Article)

Biflavonoids with cytotoxic and antibacterial activity from Ochna macrocalyx

Tang, S.; Bremner, Paul; Kortenkamp, A.; Schlage, C.; Gray, A. I.; Gibbons, S.; Heinrich, M. (Article)

Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells

Surichan, Somchaiya; Androutsopoulos, Vasilis; Sifakis, S.; Koutala, E.; Tsatsakis, A.; Arroo, R. R. J.; Boarder, M. R. (Article)

Bioautography-Guided Identification of Antimicrobial Essential Oil Components of Oregano, Cumin and Rosewood against Antibiotic Sensitive and Resistant Staphylococcus aureus, Enterococcus faecium, Escherichia coli and Pseudomonas aeruginosa

Owen, L.; White, A.; Laird, Katie (Conference)

The increase in antimicrobial resistance and decrease in antibiotics being developed has resulted in the need for new strategies to treat antibiotic resistant infections. Many Essential Oils (EOs) possess broad spectrum ...

Bioinspired bubble design for particle generation

Gunduz, Oguzhan; Ahmad, Z.; Stride, E.; Tamerler, Candan; Edirisinghe, M. (Article)

Biomedical applications of batteries

Latham, R. J.; Linford, R. G.; Schlindwein, W. S. (Article)

Bioproduction of Anticancer Podophyllotoxin and Related Aryltretralin-Lignans in Hairy Root Cultures of Linum Flavum L.

Mikac, Sara; Markulin, Lucija; Drouet, Samantha; Corbin, Cyrielle; Tungmunnithum, Duangjai; Kiani, Reza; Kabra, Atul; Abassi, Bilal Haider; Renouard, Sullivan; Fuss, Elisabeth; Hano, Christophe; Arroo, R. R. J.; Bhambra, Avninder S.; Laine, Eric (Book chapter)

Podophyllotoxin (PPT) is the unique natural precursor of Etoposide, a topoisomerase II inhibitor drug, used in more than a dozen anticancer chemotherapy treatments. Etoposide is appearing on the list of essential medicines ...

Biosynthesis of podophyllotoxin in Linum album cell cultures

Seidel, V.; Windhövel, J.; Eaton, G.; Alfermann, A. W.; Arroo, R. R. J.; Medarde, M.; Petersen, M.; Woolley, J. G. (Article)

Biotechnological Approaches for Bioremediation: In Vitro Hairy Root Culture

Malik, S.; Adrián, S.; Arroo, R. R. J.; Bonfill, M.; Mazzafera, P.; Mirjalili, M. H. (Book chapter)

Environmental contamination has become a concerning issue worldwide due to number of risks it poses to human health and ecosystem functioning. Contaminants present in soils or waters can go up through the trophic chain ...

Biotechnological approaches for producing aryltetralin lignans from Linum species

Malik, S.; Biba, O.; Gruz, J.; Arroo, R. R. J.; Strnad, M. (Article)

Biphasic change in BDNF gene expression following antidepressant drug treatment explained by differential transcript regulation

Khundakar, A. A.; Zetterstrom, T. S. C. (Article)

Biphenyl urea derivatives as selective CYP1B1 inhibitors

Siddique, Mohd Usman Mohd; Sonawane, Vinay; Horley, Neill; Williams, Ibidapo Steven; Joshi, Prashant; Bharate, Sandip B.; Jayaprakash,Venkatesan; Sinha, Barij N.; Chaudhuri, Bhabatosh; McCann, Glen J. P. (Article)

Highly selective CYP1B1 inhibitors have potential in the treatment of hormone-induced breast and prostate cancers. Mimicry of potent and selective CYP1B1 inhibitors, α-naphthoflavone and stilbenes, revealed that two ...