Browsing Leicester School of Pharmacy by Title
Now showing items 8-27 of 1197
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Absorption, Distribution, Metabolism and Excretion (ADME) of Dietary Flavones and Their Glycosides
(Conference)Epidemiological studies have long indicated a possible role for dietary flavonoids, notably flavones and flavonols, in the prevention of a range of degenerative diseases, e.g. cancer, diabetes, cardiovascular diseases and ... -
Actinometric and Φ-order photodegradation properties of anti-cancer Sunitinib.
(Article)The photodegradation reaction of Sunitinib (SUT), occurring via Z–E photoisomerization, has been evaluated in this study using the recently developed –order kinetics. In ethanol, the forward (Z E) photoreaction of SUT was ... -
Activity of Antioxidants from Crocus sativus L. Petals: Potential Preventive Effects towards Cardiovascular System
(Article)The petals of the saffron crocus (Crocus sativus L.) are considered a waste material in saffron production, but may be a sustainable source of natural biologically active substances of nutraceutical interest. The aim of ... -
Activity of DNA-targeted C8-linked pyrrolobenzodiazepine(PBD)-heterocyclic polyamide conjugates against aerobically and hypoxically grown Mycobacterium tuberculosis under acidic and neutral conditions
(Article)Mycobacterium tuberculosis (Mtb) is the aetiological agent of tuberculosis, the leading cause of death worldwide from a single infectious agent. Mtb is a highly-adaptable human pathogen that might enter a dormant non-replicating ... -
Ad libitum administration of sucrose during adolescence causes changes in dopamine neurotransmission which are partially reversed by glucagon-like peptide
(Conference)Ad libitum administration of sucrose during adolescence causes changes in dopamine neurotransmission which are partially reversed by glucagon-like peptide. Background: Overconsumption of sugar in children, associated with ... -
Adherence to cardiovascular pharmacotherapy assessed by quantitative LC-HRMS analysis of dried blood spots
(Conference)Up to ~50% of patients prescribed cardiovascular (CVD) drugs do not adhere to their prescribed regimen. Non-adherence impacts on patient health and healthcare system costs. Dried blood spot (DBS) sampling was used to collect ... -
Advanced hydrogels for treatment of diabetes
(Article)Diabetes mellitus is a chronic disease characterized by high levels of glucose in the blood, which leads to metabolic disorders with severe consequences. Today, there is no cure for diabetes. The current management for ... -
Advanced Nanoparticles in Medical Biosensors
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AFM visualization of sub-50nm polyplex disposition to the nuclear pore complex without compromising the integrity of the nuclear envelope
(Article)It has been questioned as to whether polyplexes in the cytoplasm can reach the nuclear compartment and if so in what form. By applying atomic force microscopy (AFM) to the nuclear envelope and the nuclear pore complexes, ... -
Age-related attitude to malaria and travel
(Article)