Leicester School of Pharmacy
Recent Submissions
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Molecular Composition of and Potential Health Benefits Offered by Natural East African Virgin Sunflower Oil Products: A 400 MHz 1H NMR Analysis Study
(Article)Objectives: Sunflower oil (SFO) is regularly employed for cosmetic, emollient and food frying purposes, the latter representing its foremost use globally. Therefore, full investigations of the molecular composition and ... -
Assessing the ex vivo permeation behaviour of functionalised contact lens coatings engineered using an electrohydrodynamic technique
(Article)In vitro testing alone is no longer considered sufficient evidence presented solely with respect to drug release and permeation testing. These studies are thought to be more reliable and representative when using tissue ... -
Germ's Journey Mini Brum Exhibition
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Interactive Health-Hygiene Education for Early Years: A Germ’s Journey
(Article)This study reports the findings of a mixed method research study (qualitative and quantitative) on the effectiveness of specifically developed learning resources and workshops on handwashing for children in the Early Years ... -
Physicomechanical properties of sintered scaffolds formed from porous and protein-loaded poly (DL-lactic-co-glycolic acid) microspheres for potential use in bone tissue engineering
(Article)An injectable poly(DL-lactic-co-glycolic acid) (PLGA) system comprising both porous and protein-loaded microspheres capable of forming porous scaffolds at body temperature was developed for tissue regeneration purposes. ... -
Spatiotemporal release of VEGF from biodegradable polylactic-co-glycolic acid microspheres induces angiogenesis in chick chorionic allantoic membrane assay
(Article)While vascular endothelial growth factor (VEGF) is an acknowledged potent pro-angiogenic agent there is a need to deliver it at an appropriate concentration for several days to achieve angiogenesis. The aim of this study ... -
Targeted protein delivery: carbodiimide crosslinking influences protein release from microparticles incorporated within collagen scaffolds
(Article)Tissue engineering response may be tailored via controlled, sustained release of active agents from protein-loaded degradable microparticles incorporated directly within three-dimensional (3D) ice-templated collagen ... -
Twelve Hour Longevity of the Oral Malodor-Neutralizing Capacity of an Oral Rinse Product Containing the Chlorine Dioxide Precursor Sodium Chlorite
(Article)Objectives: The objectives of this investigation were to investigate the effectiveness and longevity of an oral rinse product containing 0.10% (w/v) of the chlorine dioxide precursor sodium chlorite (1) on oral malodor in ... -
Title: Dental anxiety in first- and final-year Indian dental students
(Article)Abstract Objectives: The study aims to investigate dental anxiety in first- and final-year undergraduate dental students in India. Design: Questionnaire Study Setting: BDS Students in four University dental ... -
On the Kinetics of Solvate Formation through Mechanochemistry
(Article)Theophylline:2-pyrrolidone mono (1:1) and sesqui (2:3) solvates have been discovered through variable-amount liquid-assisted grinding (VALAG). The structures and stability of the solvates and the kinetics involved in their ... -
The International Response To Knife Crime: Researching Identification Methods To Assist The UK Response
(Conference)Knife crime is an increasing occurrence in the UK, impacting rural communities and urban areas. The September 2018 Crime Survey of England and Wales recorded 42,957 knife offences; the highest level since 2011. Personal ... -
The Cube: A Novel Approach for BPA Training and Crime Scene Reconstruction
(Conference)‘The Cube’: A Novel Approach for BPA Training and Crime Scene Reconstruction De Montfort University (Leicester, UK) offers a Chartered Society of Forensic Sciences (CSFS) accredited BSc (Hons) forensic science undergraduate ... -
Development of visualisation techniques for latent fingermarks on leather and suede
(Conference / Other)Leather and suede items are associated with diverse acquisitive and violent crimes, from petty theft and counterfeit clothing/bags to restraints and sheaths for weapons. As a consequence, they offer considerable potential ... -
Modelling the Effect of Process Parameters on the Wet Extrusion and Spheronisation of High-Loaded Nicotinamide Pellets Using a Quality by Design Approach
(Article)The aim of the present study was to develop an alternative process to spray granulation in order to prepare high loaded spherical nicotinamide (NAM) pellets by wet extrusion and spheronisation. Therefore, a quality by ... -
The synthesis of 4,6-diaryl-2-pyridones and their bioactivation in CYP1 expressing breast cancer cells
(Article)As part of a programme to develop anticancer prodrugs which are activated by cytochrome P450 (CYP)1B1, a library of 4,6-diaryl-2-pyridones was synthesised in yields of 6-60% from the corresponding chalcones. A number of ... -
Development of sustainable cotton fabrics with natural immortelle essential oil for antimicrobial and mosquito repellent functions
(Conference)Vector-borne infectious diseases, such as malaria, dengue fever, yellow fever and plague, are prevalent in subtropical regions. The malaria parasite can be spread via the bites of infected mosquitos. All travellers from ... -
Application of Texture Analysis technique in formulation development of lyophilized orally disintegrating tablets containing mannitol, polyvinylpyrrolidone and amino acids
(Article)Orally disintegrating tablets (ODTs) attract a great attention as this easy swallowing dosage form often improves patient compliance. In the current work, orally disintegrating tablets comprising mannitol, polyvinylpyrrolidone ... -
Transcriptional response of vancomycin resistant Enterococcus faecium to a synergistic antibiotic-essential oil combination: A strategy to preserve the current antibiotic repertoire?
(Conference)Background: New antimicrobials to treat Vancomycin Resistant Enterococcus faecium (VRE) infections are considered a high priority. Essential oil compounds have been shown to interact synergistically with antibiotics, and ... -
Cytosolic Glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease
(Article)Niemann-Pick type C disease (NPCD) is a neurodegenerative disease associated with increases in cellular cholesterol and glycolipids and most commonly caused by defective NPC1, a late endosomal protein. Using ratiometric ... -
PuzzlEd: RAISE
(Conference)In this interactive workshop, the HE Advance CATE (Spotlight) Award winning CrashEd team from De Montfort University will showcase our current innovative venture, PuzzlEd. Whereas CrashEd was the culmination of interdisciplinary ...
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