Dried blood spot analysis to assess medication adherence and to inform personalization of treatment
Date
2014-12
Authors
Tanna, Sangeeta
Lawson, Graham
Journal Title
Journal ISSN
ISSN
1757-6180
Volume Title
Publisher
Future Science
Peer reviewed
Yes
Abstract
Little research using dried blood spot samples to assess adherence to medication has
been reported. The World Health Organisation estimates that only half of the patients
in the developed world take their medication as prescribed. Additional costs to the
healthcare provider include wasted medicines, avoidable additional hospital visits
and non-optimum patient care. There is little evidence of information concerning
medication adherence being made available to inform clinical decision making. In this
article we explore the potential of the dried blood spot sample collection methodology
as a means of identifying medication adherence to facilitate medicines optimization
for a range of disparate diseases. Furthermore, the opportunity to personalize
healthcare for different patients by assessing the clinically necessary therapeutic level
of the relevant drugs is highlighted.
Description
Keywords
medication adherence, dried blood spot analysis
Citation
Tanna, S. and Lawson, G. (2014) Dried blood spot analysis to assess medication adherence and to inform personalization of treatment. Bioanalysis, 6 (21), pp. 2825-2838
Research Institute
Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)