Long term stability and storage of acrylic derivatised glucose responsive dextran-concanavalin A gels

Date
2013-07
Authors
Sahota, T. S.
Taylor, M. Joan
Journal Title
Journal ISSN
ISSN
DOI
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Publisher
40th Annual Meeting & Exposition of the Controlled Release Society
Peer reviewed
Yes
Abstract
The long term stability of photopolymerised acrylic derivatives of dextran and concanavalin A (con A) and dextran and con A mixtures has been shown at 20 and 37°C by rheological characterisation when stored with and without 0.1%w/w glucose. Acrylic gels were found to have a stable complex viscosity for over 730 days at 20 and 37°C indicating that over time the gel components do not undergo degradation which stored in dialysis membrane, Molecular Weight Cut Off (MWCO) 50kDa.
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Citation
Sahota, T.S. and Taylor, M.J. (2013) Long term stability and storage of acrylic derivatised glucose responsive dextran-concanavalin A gels. 40th Annual Meeting & Exposition of the Controlled Release Society
Research Institute
Leicester Institute for Pharmaceutical Innovation - From Molecules to Practice (LIPI)