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Browsing by Author "Sonawane, Vinay"
Now showing items 1-5 of 5
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Siddique, Mohd Usman Mohd ; Sonawane, Vinay ; Horley, Neill ; Williams, Ibidapo Steven ; Joshi, Prashant ; Bharate, Sandip B. ; Jayaprakash,Venkatesan ; Sinha, Barij N. ; Chaudhuri, Bhabatosh ; McCann, Glen J. P. (Article)Highly selective CYP1B1 inhibitors have potential in the treatment of hormone-induced breast and prostate cancers. Mimicry of potent and selective CYP1B1 inhibitors, α-naphthoflavone and stilbenes, revealed that two ...
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Horley, Neill ; Beresford, Kenneth J. M. ; Chawla, Tarun ; McCann, Glen J. P. ; Ruparelia, K. C. ; Gatchie, Linda ; Sonawane, Vinay ; Williams, Vinay R. ; Tan, Hoon Leong ; Joshi, Prashant ; Bharate, Sonali S. ; Kumar, Vikas ; Bharate, Sandip B. ; Chaudhuri, Bhabatosh (Article)The structure of alpha-napthoflavone (ANF), a potent inhibitor of CYP1A1 and CYP1B1, mimics the structure of chalcones. Two potent CYP1B1 inhibitors 7k (DMU2105) and 6j (DMU2139) have been identified from two series of ...
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Horley, Neill ; Beresford, Kenneth J. M. ; Kaduskar, S. ; Joshi, Prashant ; McCann, Glen J. P. ; Ruparelia, K. C. ; Williams, Ibidapo Steven ; Gatchie, Linda ; Sonawane, Vinay ; Bharate, Sandip B. ; Chaudhuri, Bhabatosh (Article)The overexpression of CYP1 family of enzymes is reported to be associated with development of human carcinomas. It has been well reported that CYP1A1 specific inhibitors prevents carcinogenesis. Herein, thirteen pyridine-4-yl ...
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Joshi, Prashant ; Sonawane, Vinay ; Williams, Ibidapo Steven ; McCann, Glen J. P. ; Gatchie, Linda ; Sharma, Rajni ; Satti, Naresh ; Chaudhuri, Bhabatosh ; Bharate, Sandip B. (Article)CYP1A1 is thought to mediate carcinogenesis in oral, lung and epithelial cancers. In order to identify a CYP1A1 inhibitor from an edible plant, 394 natural products in the IIIM's natural product repository were screened, ...
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Siddique, Mohd Usman Mohd ; McCann, Glen J. P. ; Sonawane, Vinay ; Horley, Neill ; Gatchie, Linda ; Joshi, Prashant ; Bharate, Sandip B. ; Jayaprakash,Venkatesan ; Sinha, Barij N. ; Chaudhuri, B. (Article)CYP1B1 is implicated to have a role in the development of breast, ovarian, renal, skin and lung carcinomas. It has been suggested that identification of potent and specific CYP1B1 inhibitors can lead to a novel treatment ...
Now showing items 1-5 of 5
