Highly selective CYP1B1 inhibitors have potential in the treatment
of hormone-induced breast and prostate cancers. Mimicry of
potent and selective CYP1B1 inhibitors, α-naphthoflavone and stilbenes,
revealed that two ...
The structure of alpha-napthoflavone (ANF), a potent inhibitor of CYP1A1 and CYP1B1, mimics the
structure of chalcones. Two potent CYP1B1 inhibitors 7k (DMU2105) and 6j (DMU2139) have been
identified from two series of ...
The overexpression of CYP1 family of enzymes is reported to be associated with
development of human carcinomas. It has been well reported that CYP1A1 specific
inhibitors prevents carcinogenesis. Herein, thirteen pyridine-4-yl ...
CYP1A1 is thought to mediate carcinogenesis in oral, lung and epithelial cancers. In order to identify a CYP1A1 inhibitor from an edible plant, 394 natural products in the IIIM's natural product repository were screened, ...