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    Browsing by Author "Maréchal, Jean-Didier"

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      • CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G(0)/G(1) inhibiting pRB phosphorylation. 

        Chaudhuri, B.; Aubry, C.; Mahale, S.; Wilson, A. J.; Jenkins, Paul R.; Maréchal, Jean-Didier; Sutcliffe, Michael J. (Article)
      • The design and synthesis of novel 3-[2-indol-1-yl-ethyl]-1H-indole derivatives as selective inhibitors of CDK4 

        Aubry, C.; Patel, A.; Mahale, S.; Chaudhuri, B.; Maréchal, Jean-Didier; Sutcliffe, Michael J.; Jenkins, Paul R. (Article)
      • Design, synthesis and biological activity of new CDK4-specific inhibitors, based on fascaplysin 

        Aubry, C.; Wilson, A. J.; Jenkins, Paul R.; Mahale, S.; Chaudhuri, B.; Maréchal, Jean-Didier; Sutcliffe, Michael J. (Article)
      • Inhibition of cancer cell growth by cyclin dependent kinase 4 inhibitors synthesized based on the structure of fascaplysin. 

        Mahale, S.; Aubry, C.; Jenkins, Paul R.; Maréchal, Jean-Didier; Sutcliffe, Michael J.; Chaudhuri, B. (Article)
      • New fascaplysin-based CDK4-specific inhibitors: design, synthesis and biological activity. 

        Chaudhuri, B.; Aubry, C.; Jenkins, Paul R.; Mahale, S.; Maréchal, Jean-Didier; Sutcliffe, Michael J. (Article)

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